DE NOVO ORFS IN DROSOPHILA ARE IMPORTANT TO ORGANISMAL FITNESS AND EVOLVED RAPIDLY FROM PREVIOUSLY NON-CODING SEQUENCES.

De novo ORFs in Drosophila are important to organismal fitness and evolved rapidly from previously non-coding sequences.

How non-coding DNA gives rise to new protein-coding genes (de novo genes) is not well understood.Recent work has revealed the origins and functions of a few de novo genes, but common principles governing the evolution or biological roles of these genes are unknown.To better define these principles, we performed a parallel analysis of the evolution

read more

Inhibitory networks of the amygdala for emotional memory

The amygdala is important for emotional memory, including learned fear.A Card Readers number of studies for amygdala neural circuits that underlie fear conditioning have elucidated specific cellular and molecular mechanisms of emotional memory.Recent technical advances such as optogenetic approaches have not only confirmed the importance of excitat

read more